As a microbiology professional research institution with the characteristics and advantages of tropical and subtropical regions, it has a strong demand for microbiology in the social and economic development of the country and Guangdong Province. It has long been focused on microbial resources, microbial and ecological environment, food safety and tropical and subtropical characteristics. Relevant foundations, application foundations and public welfare research on health, etc., carry out research on common key technologies and exploration of reserve frontier technologies to support the sustainable development of biotechnology-related industries. The State Key Laboratory for the Establishment of Applied Microorganisms in South China, the National Chemical Environmental Safety Assessment Service Center of Guangzhou, the National Experimental Base of the National Bio-Industry Base, and the National Patented Species Collection Organization-Guangdong Provincial Microbial Culture Collection Center, South China A large number of national and provincial-level scientific and technological innovation platforms, such as the large fungal specimen museum in the region (the second largest in the country) and the Guangdong Provincial Drinking Water Safety Emergency Technology Research Center. At present, the institute has formed four major domestic disciplines such as resource microbiology, environmental microbiology, analytical microbiology and mold rot microbiology. With the ability to train doctoral and postgraduate students, two post-doctoral research stations approved by the Ministry of Human Resources and Social Security were established. Guangdong Microbiology Society, Guangdong Edible Fungus Industry Association, Guangdong Biotechnology Productivity Promotion Center, and Guangdong Provincial Quality Supervision Edible Fungus Inspection Station are all affiliated to the Institute. At the same time, he is also the vice president unit of China Edible Fungus Association.

In the past 50 years since its establishment, the Institute has made remarkable achievements in technological innovation, key technologies common to the industry, and the transfer and transformation of scientific and technological services and scientific and technological achievements. In terms of scientific and technological innovation, it has undertaken the national "973" plan, the national "863" plan, national major scientific and technological research, national science and technology support, international cooperation, the National Natural Science Foundation, the transformation of agricultural science and technology achievements, and the national bio-high-tech industrialization demonstration project. Major key scientific and technological projects such as the Ministry of Education's industry-university research, Guangdong-Hong Kong bidding project and provincial fund team, major key scientific and technological projects in the province, science and technology aid Tibet, and major key science and technology projects in Guangzhou. A total of 152 scientific and technological innovations were obtained, including 76 internationally advanced and leading levels; 111 national and provincial-level achievement awards, including 7 national-level achievement awards and 16 provincial-level first-class awards; 209 pieces of authorized patents, including 195 invention patents. In 2010, it was recognized as “Guangdong Province Intellectual Property Demonstration Unit” and “National Enterprise Intellectual Property Pilot Unit”; hosted and participated in more than 110 revisions of national, industry and local standards; published papers in core academic journals at home and abroad 2000 A number of articles, publishing technology monographs 36. He was awarded the Outstanding Team Award by the “11th Five-Year” National Science and Technology Plan.                       

The key laboratory for the preservation and application of strains in Guangdong Province, which was built by the Institute, was awarded the Guangdong Provincial Excellent Key Laboratory four times in 2000, 2003, 2006 and 2010; Guangdong Provincial Microbiology Application New Technology Public Laboratory In 2008, it passed the acceptance of the Guangdong Provincial Department of Science and Technology with excellent results. The Guangdong Key Laboratory of Applied Microbiology in Guangdong Province was established in 2009 on the basis of the Guangdong Provincial Key Laboratory of Culture Collection and Application and the Guangdong Provincial Microbiology Application New Technology Public Laboratory. The Ministry of Science and Technology approved the establishment of a national key laboratory cultivation base jointly established by the Ministry of Science and Technology. In April 2012, it passed the expert acceptance organized by the Ministry of Science and Technology. In March 2013, it was successfully promoted to the Ministry of Science and Technology to form a microbial country in South China. Main lab. The main research directions of the State Key Laboratory are “Diversity and Utilization of Microbial Resources in Tropical and Subtropical Regions, Environmental Microbial and Regional Ecological Security, Monitoring and Control of Harmful Microorganisms”. At present, the laboratory has an experimental area of ??6,750 square meters, including public laboratories, large instrument rooms, South China Microbial Resource Center (including specimen library and strain collection center), environmental microbiology laboratory, microbial detection and control laboratory, mold and microbial experiment. Laboratory, physiological and molecular mechanism of food and medicinal bacteria, pre-industrial laboratory and public service platform for animal experiment technology; 127 sets of various instruments and equipment of more than 100,000 yuan, the original value of 53.38 million yuan, of which 300,000 yuan 49 sets of the above equipment, including flow cytometry, transmission electron microscope, scanning electron microscope, laser confocal microscope, atomic force microscope, molecular interaction instrument, high-throughput gene sequencer, digital PCR system, ultra-high performance liquid chromatography , microbial electrolysis respirometer, mass spectrometer, gas chromatograph, inductively coupled plasma mass spectrometer, high performance triple triple quadrupole liquid chromatography system, high speed refrigerated centrifuge, automatic microbial identification system, etc. Part of it has been purchased since 2008, and the overall equipment has reached the international advanced level. Fully equipped laboratory and research equipment requirements at the molecular level, the cellular level and gene level.